Similac® Advance® 20

Similac^® Advance^®

Infant formula with iron

❮ ❯

Similac^® Advance^®

Infant formula with iron

SIMILAC ADVANCE is a 20 Cal/fl oz, nutritionally complete, milk-based, iron-fortified infant formula for use as a supplement or alternative to breastfeeding.

DOWNLOAD GUIDE

CONTACT A REP

Insurance Coverage May Apply – Learn More.

Hospitals and institutions can order Abbott Nutrition products by calling 800-551-5838, Monday – Friday, 8:00 a.m. to 5:30 p.m. EST.

Established Abbott accounts can order online at e-Abbott.com.

Values listed below are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

List Number	Item	Market
53363	Similac Advance Ready to Feed / 32 fl oz (946 mL) Bottle / 6 ct	Retail
56973	Similac Advance Concentrated Liquid / 13 fl oz (384 mL) Can / 12 ct	Retail
68084	Similac Advance Powder / 20.6 oz (584 g) Simplepac/ 6 ct	Retail
58585	Similac Advance Powder / 30.8 oz (873 g) Can / 6 ct	Retail
55957	Similac Advance Powder / 12.4 oz (352 g) Can / 6 ct	Retail

Hospitals and institutions can order Abbott Nutrition products by calling 800-551-5838, Monday – Friday, 8:00 a.m. to 5:30 p.m. EST.

100 Cal (5 fl oz)

Nutrition Data

	Amount Per Serving	%DV
Calories	100
Volume, mL	148
Protein, g	2.07
Fat, g	5.4
Carbohydrate, g	11.2
Water, g	134
Linoleic Acid, mg	1000
Potential Renal Solute Load, mOsm	18.7

Vitamins

	Amount Per Serving	%DV
Vitamin A, IU	300
Vitamin D, IU	60
Vitamin E, IU	1.5
Vitamin K, mcg	8
Thiamin (Vitamin B1), mcg	100
Riboflavin (Vitamin B2), mcg	150
Vitamin B6, mcg	60
Vitamin B12, mcg	0.25
Niacin, mcg	1050
Folic Acid (Folacin), mcg	15
Pantothenic Acid, mcg	450
Biotin, mcg	4.4
Vitamin C (Ascorbic Acid), mg	9
Choline, mg	24
Inositol, mg	24

Minerals

	Amount Per Serving	%DV
Calcium, mg	78
Calcium, mEq	3.9
Phosphorus, mg	42
Magnesium, mg	6
Iron, mg	1.8
Zinc, mg	0.75
Manganese, mcg	5
Copper, mcg	90
Iodine, mcg	15
Selenium, mcg	2
Sodium, mg	24
Sodium, mEq	1
Potassium, mg	105
Potassium, mEq	2.7
Chloride, mg	65
Chloride, mEq	1.8

100 Cal Unreconstituted^*

Nutrition Data

	Amount Per Serving	%DV
Calories	100
Volume, mL	74
Protein, g	2.07
Fat, g	5.4
Carbohydrate, g	11.2
Water, g	60
Linoleic Acid, mg	1000
Potential Renal Solute Load, mOsm	18.7

Vitamins

	Amount Per Serving	%DV
Vitamin A, IU	300
Vitamin D, IU	60
Vitamin E, IU	1.5
Vitamin K, mcg	8
Thiamin (Vitamin B1), mcg	100
Riboflavin (Vitamin B2), mcg	150
Vitamin B6, mcg	60
Vitamin B12, mcg	0.25
Niacin, mcg	1050
Folic Acid (Folacin), mcg	15
Pantothenic Acid, mcg	450
Biotin, mcg	4.4
Vitamin C (Ascorbic Acid), mg	9
Choline, mg	24
Inositol, mg	24

Minerals

	Amount Per Serving	%DV
Calcium, mg	78
Calcium, mEq	3.9
Phosphorus, mg	42
Magnesium, mg	6
Iron, mg	1.8
Zinc, mg	0.75
Manganese, mcg	5
Copper, mcg	90
Iodine, mcg	15
Selenium, mcg	2
Sodium, mg	24
Sodium, mEq	1
Potassium, mg	105
Potassium, mEq	2.7
Chloride, mg	65
Chloride, mEq	1.8

*Values reflect unreconstituted formula. Add water before using.

100 Cal (5 fl oz, prepared as directed)

Nutrition Data

	Amount Per Serving	%DV
Calories	100
Volume, mL	148
Protein, g	2.07
Fat, g	5.6
Carbohydrate, g	10.7
Water, g	133
Linoleic Acid, mg	1000

Vitamins

	Amount Per Serving	%DV
Vitamin A, IU	300
Vitamin D, IU	60
Vitamin E, IU	1.5
Vitamin K, mcg	8
Thiamin (Vitamin B1), mcg	100
Riboflavin (Vitamin B2), mcg	150
Vitamin B6, mcg	60
Vitamin B12, mcg	0.25
Niacin, mcg	1050
Folic Acid (Folacin), mcg	15
Pantothenic Acid, mcg	450
Biotin, mcg	4.4
Vitamin C (Ascorbic Acid), mg	9
Choline, mg	24
Inositol, mg	24

Minerals

	Amount Per Serving	%DV
Calcium, mg	78
Calcium, mEq	3.9
Phosphorus, mg	42
Magnesium, mg	6
Iron, mg	1.8
Zinc, mg	0.75
Manganese, mcg	5
Copper, mcg	90
Iodine, mcg	15
Selenium, mcg	2
Sodium, mg	24
Sodium, mEq	1
Potassium, mg	105
Potassium, mEq	2.7
Chloride, mg	65
Chloride, mEq	1.8

1000 mL (1.1 QT)

Nutrition Data

	Amount Per Serving	%DV
Calories	676
Volume, mL	1000
Protein, g	13.99
Fat, g	36.49
Carbohydrate, g	75.68
Water, g	905
Linoleic Acid, mg	6757
Potential Renal Solute Load, mOsm	126.7

Vitamins

	Amount Per Serving	%DV
Vitamin A, IU	2027
Vitamin D, IU	405
Vitamin E, IU	10.1
Vitamin K, mcg	54.1
Thiamin (Vitamin B1), mcg	676
Riboflavin (Vitamin B2), mcg	1014
Vitamin B6, mcg	405
Vitamin B12, mcg	1.69
Niacin, mcg	7095
Folic Acid (Folacin), mcg	101.4
Pantothenic Acid, mcg	3041
Biotin, mcg	29.7
Vitamin C (Ascorbic Acid), mg	60.8
Choline, mg	162.2
Inositol, mg	162.2

Minerals

	Amount Per Serving	%DV
Calcium, mg	527
Calcium, mEq	26.4
Phosphorus, mg	284
Magnesium, mg	40.5
Iron, mg	12.16
Zinc, mg	5.07
Manganese, mcg	33.8
Copper, mcg	608
Iodine, mcg	101
Selenium, mcg	14
Sodium, mg	162
Sodium, mEq	7
Potassium, mg	709
Potassium, mEq	18.2
Chloride, mg	439
Chloride, mEq	12.4

100 Cal (5 fl oz, prepared as directed)

Nutrition Data

	Amount Per Serving	%DV
Calories	100
Volume, mL	148
Protein, g	2.07
Fat, g	5.4
Carbohydrate, g	11.2
Water, g	133
Linoleic Acid, mg	1000
Potential Renal Solute Load, mOsm	18.7

Vitamins

	Amount Per Serving	%DV
Vitamin A, IU	300
Vitamin D, IU	60
Vitamin E, IU	1.5
Vitamin K, mcg	8
Thiamin (Vitamin B1), mcg	100
Riboflavin (Vitamin B2), mcg	150
Vitamin B6, mcg	60
Vitamin B12, mcg	0.25
Niacin, mcg	1050
Folic Acid (Folacin), mcg	15
Pantothenic Acid, mcg	450
Biotin, mcg	4.4
Vitamin C (Ascorbic Acid), mg	9
Choline, mg	24
Inositol, mg	24

Minerals

	Amount Per Serving	%DV
Calcium, mg	78
Calcium, mEq	3.9
Phosphorus, mg	42
Magnesium, mg	6
Iron, mg	1.8
Zinc, mg	0.75
Manganese, mcg	5
Copper, mcg	90
Iodine, mcg	15
Selenium, mcg	2
Sodium, mg	24
Sodium, mEq	1
Potassium, mg	105
Potassium, mEq	2.7
Chloride, mg	65
Chloride, mEq	1.8

1000 mL (1.1 QT, prepared as directed)

Nutrition Data

	Amount Per Serving	%DV
Calories	676
Volume, mL	1000
Protein, g	14
Fat, g	37.87
Carbohydrate, g	72.36
Water, g	899
Linoleic Acid, mg	6763

Vitamins

	Amount Per Serving	%DV
Vitamin A, IU	2029
Vitamin D, IU	406
Vitamin E, IU	10.1
Vitamin K, mcg	54.1
Thiamin (Vitamin B1), mcg	676
Riboflavin (Vitamin B2), mcg	1014
Vitamin B6, mcg	406
Vitamin B12, mcg	1.69
Niacin, mcg	7101
Folic Acid (Folacin), mcg	101.4
Pantothenic Acid, mcg	3043
Biotin, mcg	29.8
Vitamin C (Ascorbic Acid), mg	60.9
Choline, mg	162.3
Inositol, mg	162.3

Minerals

	Amount Per Serving	%DV
Calcium, mg	528
Calcium, mEq	26.4
Phosphorus, mg	284
Magnesium, mg	40.6
Iron, mg	12.17
Zinc, mg	5.07
Manganese, mcg	33.8
Copper, mcg	609
Iodine, mcg	101
Selenium, mcg	14
Sodium, mg	162
Sodium, mEq	7
Potassium, mg	710
Potassium, mEq	18.2
Chloride, mg	440
Chloride, mEq	12.4

1000 mL (Prepared as directed)

Nutrition Data

	Amount Per Serving	%DV
Calories	676
Volume, mL	1000
Protein, g	13.99
Fat, g	36.49
Carbohydrate, g	75.68
Water, g	905
Linoleic Acid, mg	6757
Potential Renal Solute Load, mOsm	126.7

Vitamins

	Amount Per Serving	%DV
Vitamin A, IU	2027
Vitamin D, IU	405
Vitamin E, IU	10.1
Vitamin K, mcg	54.1
Thiamin (Vitamin B1), mcg	676
Riboflavin (Vitamin B2), mcg	1014
Vitamin B6, mcg	405
Vitamin B12, mcg	1.69
Niacin, mcg	7095
Folic Acid (Folacin), mcg	101.4
Pantothenic Acid, mcg	3041
Biotin, mcg	29.7
Vitamin C (Ascorbic Acid), mg	60.8
Choline, mg	162.2
Inositol, mg	162.2

Minerals

	Amount Per Serving	%DV
Calcium, mg	527
Calcium, mEq	26.4
Phosphorus, mg	284
Magnesium, mg	40.5
Iron, mg	12.16
Zinc, mg	5.07
Manganese, mcg	33.8
Copper, mcg	608
Iodine, mcg	101
Selenium, mcg	14
Sodium, mg	162
Sodium, mEq	7
Potassium, mg	709
Potassium, mEq	18.2
Chloride, mg	439
Chloride, mEq	12.4

Features

OptiGRO® is our exclusive blend of DHA, lutein and vitamin E: these important ingredients are found in breast milk. <ul> <li>DHA for brain and eye development.</li> <li>Lutein to support eye health.</li> <li>Vitamin E; an important nutrient found in breast milk to support developing cells.</li> </ul>

Our exclusive formula has: <ul> <li>Calcium for strong bones - no palm olein oil.</li> <li>Nucleotides to help support the immune system.</li> <li>Prebiotics to help promote digestive health.</li> <li>Carotenoids like those naturally found in breast milk.</li> </ul>

Clinically proven tolerance in newborns.1

Clinically shown to support greater calcium absorption* for strong bones.2,3

Gluten-free.

Kosher made with dairy ingredients.

Halal.

Precautions

Not for infants or children with galactosemia.

Never use a microwave oven to warm formula. Serious burns can result.

Powdered infant formulas are not sterile and should not be fed to premature infants or infants who might have immune problems unless directed and supervised by your baby's doctor.

* Similac® with Iron vs Enfamil® with Iron. Enfamil is not a trademark of Abbott Laboratories.

1 Lloyd B, et al. Pediatrics. 1999;103(1):1-6.

2 Nelson SE, et al. J Am Coll Nutr. 1998;17(4):327-332.

3 Koo W, et al. Pediatrics. 2003;111:1017-1023.

Unflavored Liquid

Unflavored Concentrated Liquid

Unflavored Powder

Water, Nonfat Milk, Lactose, High Oleic Safflower Oil, Soy Oil, Coconut Oil, Galactooligosaccharides^*, Whey Protein Concentrate. Less than 0.5% of: Schizochytrium Sp. Oil^†, M. Alpina Oil^‡, Beta-Carotene, Lutein, Ascorbic Acid, Calcium Carbonate, Potassium Citrate, Soy Lecithin, Monoglycerides, Potassium Chloride, Carrageenan, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Taurine, Calcium Phosphate, Potassium Phosphate, Inositol, Zinc Sulfate, Niacinamide, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, L-Carnitine, Riboflavin, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Salt, Potassium Iodide, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).
^* Prebiotic
^† Source of DHA.
^‡ Source of ARA.

Water, Nonfat Milk, Lactose, High Oleic Safflower Oil, Soy Oil, Coconut Oil, Galactooligosaccharides^*, Whey Protein Concentrate. Less than 1.0% of: Schizochytrium Sp. Oil^†, M. Alpina Oil^‡, Beta-Carotene, Lutein, Ascorbic Acid, Calcium Carbonate, Potassium Citrate, Soy Lecithin, Monoglycerides, Potassium Chloride, Carrageenan, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Taurine, Calcium Phosphate, Potassium Phosphate, Inositol, Zinc Sulfate, Niacinamide, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, L-Carnitine, Riboflavin, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Salt, Potassium Iodide, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).
^* Prebiotic
^† Source of DHA.
^‡ Source of ARA.

Nonfat Milk, Lactose, High Oleic Safflower Oil, Whey Protein Concentrate, Soy Oil, Coconut Oil, Galactooligosaccharides^*. Less than 2% of: Schizochytrium Sp. Oil^†, M. Alpina Oil^‡, Beta-Carotene, Lutein, Potassium Citrate, Calcium Carbonate, Ascorbic Acid, Soy Lecithin, Potassium Chloride, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Ascorbyl Palmitate, Salt, Taurine, Inositol, Zinc Sulfate, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, L-Carnitine, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Calcium Phosphate, Potassium Phosphate, Potassium Iodide, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).
^* Prebiotic
^† Source of DHA.
^‡ Source of ARA.

Contains milk and soy ingredients.

Preparation

Instructions for Use:

Powder
Your baby's health depends on carefully following these directions. Proper hygiene, handling and storage are important when preparing infant formula. Failure to follow these directions could result in severe harm. Ask your baby's doctor if you need to use cooled, boiled water for mixing and if you need to boil (sterilize) bottles, nipples and rings before use.

Wash your hands, surfaces and utensils. Pour water into clean bottle.
Add 1 unpacked level scoop (8.7 g) to each 2 fl oz of water. Return dry scoop to can.
Cap bottle; shake well; attach clean nipple. Once feeding begins, use within 1 hour or discard.

Ready to Feed

Your baby's health depends on carefully following these directions. Failure to follow these directions could result in severe harm. Ask your baby's doctor if you need to boil (sterilize) bottles, nipples and rings before use.

Do not use if band around cap or inner foil seal is damaged.
Do not add water.
Shake very well before each use.
Remove protective band, twist off and clean cap.
Invert cap; press down to pierce foil, then turn cap a half turn.
Remove foil.
Pour formula into bottle; attach clean nipple.
Once feeding begins, use within 1 hour or discard.
Prepare and feed all formula from the 1-QT container within 3 days after opening.

Concentrated Liquid
Your baby's health depends on carefully following these directions. Failure to follow these directions could result in severe harm. Ask your baby's doctor if you need to use cooled, boiled water for mixing and if you need to boil (sterilize) bottles, nipples and rings before use.

Rinse can lid; shake very well; open with a clean punch-type opener.
Pour equal amounts of formula and water into bottle.
Attach nipple; swirl gently to mix.
Once feeding begins, use within 1 hour or discard.

Storage & Handling

Instructions for Use:

Powder

Once mixed, store bottles in refrigerator and feed to baby within 24 hours.
Store unopened or opened container at room temperature; avoid extreme temperatures.
Use opened can contents within 1 month.

Ready to Feed

Once opened, store quart bottle in refrigerator
Store prepared bottles in refrigerator and feed to baby within 48 hours.
Store unopened containers at room temperature; avoid extreme temperatures.
Do not reuse container.

Concentrated Liquid

Cover opened cans and prepared formula not used immediately. Store in refrigerator and feed to baby within 48 hours.
Store unopened cans at room temperature; avoid extreme temperatures.

Similac^® Advance^®

Infant formula with iron

SIMILAC ADVANCE is a 20 Cal/fl oz, nutritionally complete, milk-based, iron-fortified infant formula for use as a supplement or alternative to breastfeeding.

Features

OptiGRO® is our exclusive blend of DHA, lutein and vitamin E: these important ingredients are found in breast milk. <ul> <li>DHA for brain and eye development.</li> <li>Lutein to support eye health.</li> <li>Vitamin E; an important nutrient found in breast milk to support developing cells.</li> </ul>
Our exclusive formula has: <ul> <li>Calcium for strong bones - no palm olein oil.</li> <li>Nucleotides to help support the immune system.</li> <li>Prebiotics to help promote digestive health.</li> <li>Carotenoids like those naturally found in breast milk.</li> </ul>
Clinically proven tolerance in newborns.1
Clinically shown to support greater calcium absorption* for strong bones.2,3
Gluten-free.
Kosher made with dairy ingredients.
Halal.

* Similac® with Iron vs Enfamil® with Iron. Enfamil is not a trademark of Abbott Laboratories.

1 Lloyd B, et al. Pediatrics. 1999;103(1):1-6.

2 Nelson SE, et al. J Am Coll Nutr. 1998;17(4):327-332.

3 Koo W, et al. Pediatrics. 2003;111:1017-1023.

Safety Precautions

Not for infants or children with galactosemia.

Never use a microwave oven to warm formula. Serious burns can result.

Powdered infant formulas are not sterile and should not be fed to premature infants or infants who might have immune problems unless directed and supervised by your baby's doctor.

Availability

List Number	Item
53363	Similac Advance Ready to Feed / 32 fl oz (946 mL) Bottle / 6 ct
56973	Similac Advance Concentrated Liquid / 13 fl oz (384 mL) Can / 12 ct
68084	Similac Advance Powder / 20.6 oz (584 g) Simplepac/ 6 ct
58585	Similac Advance Powder / 30.8 oz (873 g) Can / 6 ct
55957	Similac Advance Powder / 12.4 oz (352 g) Can / 6 ct

Ingredients

Unflavored Liquid

Unflavored Concentrated Liquid

Unflavored Powder

Contains milk and soy ingredients.

Nutrition Information

	100 Cal (5 fl oz)
	Value%DV

	100 Cal Unreconstituted^*
	Value%DV

	100 Cal (5 fl oz, prepared as directed)
	Value%DV

	1000 mL (1.1 QT)
	Value%DV

	100 Cal (5 fl oz, prepared as directed)
	Value%DV

	1000 mL (1.1 QT, prepared as directed)
	Value%DV

	1000 mL (Prepared as directed)
	Value%DV

*Values reflect unreconstituted formula. Add water before using.

Preparation

Instructions for Use:

Wash your hands, surfaces and utensils. Pour water into clean bottle.
Add 1 unpacked level scoop (8.7 g) to each 2 fl oz of water. Return dry scoop to can.
Cap bottle; shake well; attach clean nipple. Once feeding begins, use within 1 hour or discard.

Ready to Feed

Do not use if band around cap or inner foil seal is damaged.
Do not add water.
Shake very well before each use.
Remove protective band, twist off and clean cap.
Invert cap; press down to pierce foil, then turn cap a half turn.
Remove foil.
Pour formula into bottle; attach clean nipple.
Once feeding begins, use within 1 hour or discard.
Prepare and feed all formula from the 1-QT container within 3 days after opening.

Rinse can lid; shake very well; open with a clean punch-type opener.
Pour equal amounts of formula and water into bottle.
Attach nipple; swirl gently to mix.
Once feeding begins, use within 1 hour or discard.

Storage & Handling

Instructions for Use:

Powder

Once mixed, store bottles in refrigerator and feed to baby within 24 hours.
Store unopened or opened container at room temperature; avoid extreme temperatures.
Use opened can contents within 1 month.

Ready to Feed

Once opened, store quart bottle in refrigerator
Store prepared bottles in refrigerator and feed to baby within 48 hours.
Store unopened containers at room temperature; avoid extreme temperatures.
Do not reuse container.

Concentrated Liquid

Cover opened cans and prepared formula not used immediately. Store in refrigerator and feed to baby within 48 hours.
Store unopened cans at room temperature; avoid extreme temperatures.


	Abbott Nutrition Abbott Laboratories Columbus, OH 43219 1-800-227-5767	For more information contact your Abbott Nutrition Representative or visit: www.abbottnutrition.com	© 2022 Abbott Laboratories Inc. Last updated: MM/DD/YYYY	Page of

Abbott Nutrition Abbott Laboratories
Columbus, OH 43219

1-800-227-5767

For more information contact your
Abbott Nutrition Representative or visit:

www.abbottnutrition.com

Similac® Advance®

Infant formula with iron

Similac® Advance®

Infant formula with iron

100 Cal (5 fl oz)

Nutrition Data

Vitamins

Minerals

100 Cal Unreconstituted*

Nutrition Data

Vitamins

Minerals

100 Cal (5 fl oz, prepared as directed)

Nutrition Data

Vitamins

Minerals

1000 mL (1.1 QT)

Nutrition Data

Vitamins

Minerals

100 Cal (5 fl oz, prepared as directed)

Nutrition Data

Vitamins

Minerals

1000 mL (1.1 QT, prepared as directed)

Nutrition Data

Vitamins

Minerals

1000 mL (Prepared as directed)

Nutrition Data

Vitamins

Minerals

Features

Precautions

Unflavored Liquid

Unflavored Concentrated Liquid

Unflavored Powder

Preparation

Storage & Handling

Similac® Advance®

Similac® Advance®

Infant formula with iron

Features

Safety Precautions

Availability

Ingredients

Unflavored Liquid

Unflavored Concentrated Liquid

Unflavored Powder

Nutrition Information

Preparation

Storage & Handling

Page of

Looking for More? We're Here to Help

Site Pages

Abbott

You are about to exit this site for another site.

Similac^® Advance^®

Similac^® Advance^®

100 Cal Unreconstituted^*

Similac^® Advance^®

Similac^® Advance^®