Similac® Special Care® 24 High Protein

Similac® Special Care® 24 High Protein

Premature high protein infant formula with iron
  • A 24 Cal/fl oz iron-fortified feeding for growing, low-birth-weight infants and premature infants who may need extra protein to help support growth.
  • Use under medical supervision.

  • OptiGRO™ is our exclusive blend of DHA, lutein and vitamin E: these important ingredients are found in breast milk.
    • DHA for brain and eye development.
    • Lutein to support eye health.
    • Vitamin E, an important nutrient found in breast milk to support developing cells.
  • 3.3 g of protein/100 Cal, 10% more protein than Similac Special Care 24.
  • Designed as a liquid option to meet the higher protein needs of very-low-birth-weight preterm infants.
  • When fed at 120 Cal/kg/day, meets the recommended 4 g protein/kg/day for very-low-birth-weight infants.1,2,3,4
  • Lutein, a carotenoid naturally found in colostrum and human milk, has been shown to help support eye health in the the preterm infant.5,6,7,8
  • Calcium: phosphorus content and ratio (1.8:1) supports intrauterine accretion rates.9
  • Approximately 2 mg iron/kg body weight per day when fed at 120 Cal/kg body weight per day.
  • Gluten-free.
  • Halal.
  • Kosher.


  • Very-low-birthweight infants are particularly susceptible to gastrointestinal complications; therefore, feeding should be initiated cautiously.
  • Tolerance to enteral feedings should be confirmed by initially offering small volumes of formula followed by cautious progression to higher caloric feedings.
  • Spitting up, abdominal distension, abnormal stools or stool patterns, excessive gastric residuals, or other signs of intestinal dysfunction have been associated with enteral feeding before the intestinal tract is ready to accommodate the regimen. At first signs of these problems, enteral feeding should be slowed or discontinued.
  • Not intended for feeding low-birth-weight infants after they reach a weight of 3600 g (approximately 8 lb) or as directed by a physician.
  • Never use a microwave oven to warm formula. Serious burns can result.
1 Ziegler EE. J Pediatr Gastroenterol Nutr 2007;45:170-174.
2 Klein CJ. J Nutr 2002;132:1395S-1577S.
3 Kleinman RE, Greer FR (eds): Pediatric Nutrition, 7th ed. Elk Grove Village, IL: American Academy of Pediatrics: 2014:93.
4 Canadian Pediatric Society. CMAJ 1995;152(11):1765-1785.
5 Canfield LM, et al. Eur J Nutr 2003;42:133-141.
6 Schweigert FJ, et al. Eur J Nutr 2004;43:39-44.
7 Patton S, et al. Lipids 1990;25:159-165.
8 Rubin LP, et al. J Perinatol 2012;32:418-424.
9 Mize et al. Am J Clin Nutr 1995;62:385-391.
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List Number Item
56271 Similac Special Care 24 High Protein Ready to Feed / 2-fl-oz (59-mL) bottle / 48 ct


Unflavored Ready to Feed

  • Similac Special Care 24 High Protein Ready to Feed / 2-fl-oz (59-mL) bottle / 48 ct

Serving Size: 100 Cal (4.2 fl oz)

Amount Per Serving % DV % RDI
Nutrient Data
Calories: 100    
Volume, mL: 124    
Protein, g: 3.3    
Fat, g: 5.43    
Carbohydrate, g: 10.0    
Water, g: 109    
Linoleic Acid, mg: 700    
Potential Renal Solute Load, mOsm: 29.5    
Vitamin A, IU: 1250    
Vitamin D, IU: 150    
Vitamin E, IU: 4.0    
Vitamin K, mcg: 12    
Thiamin (Vitamin B1), mcg: 250    
Riboflavin (Vitamin B2), mcg: 620    
Vitamin B6, mcg: 250    
Vitamin B12, mcg: 0.55    
Niacin, mcg: 5000    
Folic Acid (Folacin), mcg: 37    
Pantothenic Acid, mcg: 1900    
Biotin, mcg: 37    
Vitamin C (Ascorbic Acid), mg: 37    
Choline, mg: 10    
Inositol, mg: 40    
Calcium, mg: 180    
Calcium, mEq: 9.0    
Phosphorus, mg: 100    
Magnesium, mg: 12    
Iron, mg: 1.8    
Zinc, mg: 1.5    
Manganese, mcg: 12    
Copper, mcg: 250    
Iodine, mcg: 6    
Selenium, mcg: 2    
Sodium, mg: 43    
Sodium, mEq: 1.9    
Potassium, mg: 129    
Potassium, mEq: 3.3    
Chloride, mg: 81    
Chloride, mEq: 2.3    

Serving Size: 1000 mL (1.1 QT)

Amount Per Serving % DV % RDI
Nutrient Data
Calories: 812    
Volume, mL: 1000    
Protein, g: 26.8    
Fat, g: 44.07    
Carbohydrate, g: 81    
Water, g: 885    
Linoleic Acid, mg: 5681    
Potential Renal Solute Load, mOsm: 240    
Vitamin A, IU: 10144    
Vitamin D, IU: 1217    
Vitamin E, IU: 32.5    
Vitamin K, mcg: 97.4    
Thiamin (Vitamin B1), mcg: 2029    
Riboflavin (Vitamin B2), mcg: 5032    
Vitamin B6, mcg: 2029    
Vitamin B12, mcg: 4.46    
Niacin, mcg: 40578    
Folic Acid (Folacin), mcg: 300    
Pantothenic Acid, mcg: 15419    
Biotin, mcg: 300    
Vitamin C (Ascorbic Acid), mg: 300    
Choline, mg: 81    
Inositol, mg: 325    
Calcium, mg: 1461    
Calcium, mEq: 72.9    
Phosphorus, mg: 812    
Magnesium, mg: 97.4    
Iron, mg: 14.6    
Zinc, mg: 12.17    
Manganese, mcg: 97    
Copper, mcg: 2029    
Iodine, mcg: 49    
Selenium, mcg: 16    
Sodium, mg: 349    
Sodium, mEq: 15.2    
Potassium, mg: 1047    
Potassium, mEq: 26.8    
Chloride, mg: 657    
Chloride, mEq: 18.6    

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Unflavored Ready to Feed

  • Similac Special Care 24 High Protein Ready to Feed / 2-fl-oz (59-mL) bottle / 48 ct

Water, Nonfat Milk, Corn Syrup Solids, Medium-Chain Triglycerides, Whey Protein Concentrate, Lactose, Soy Oil, Coconut Oil. Less than 0.5% of: C. Cohnii Oil, M. Alpina Oil, Beta-Carotene, Lutein, Calcium Phosphate, Ascorbic Acid, Potassium Citrate, Calcium Carbonate, Soy Lecithin, Monoglycerides, Magnesium Chloride, m-Inositol, Sodium Citrate, Carrageenan, Potassium Hydroxide, Ferrous Sulfate, Choline Bitartrate, Taurine, Choline Chloride, Niacinamide, L-Carnitine, Zinc Sulfate, Potassium Chloride, Salt, Potassium Phosphate, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Vitamin A Palmitate, Cupric Sulfate, Riboflavin, Thiamine Chloride Hydrochloride, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Biotin, Phylloquinone, Sodium Selenate, Vitamin D3, Cyanocobalamin, and Nucleotides (Cytidine 5’-Monophosphate, Disodium Guanosine 5’-Monophosphate, Disodium Uridine 5’-Monophosphate, Adenosine 5’-Monophosphate).
Contains milk and soy ingredients.
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  • Can be mixed to a variety of caloric densities using the Liqui-Mix® System. Follow physician's instructions.

  • Instructions for Use:
    The health of the infant depends on carefully following the directions for preparation and use. Proper hygiene, handling and storage are important when preparing infant formula.
    • Do not add water.
    • Shake very well.
    • Do not use if breakaway ring is missing or broken.
    • Twist off cap.
    • Twist on nipple and ring.
    • Pour desired amount into feeding container (Volu-Feed or syringe) or attach clean, single-use nipple and ring (not included). Use sterile nipple and ring if directed.
    • Once oral feeding begins, use within one hour or discard.
    • If signs of intolerance develop, slow feeding or discontinue.

    Can be mixed to a variety of caloric densities using the Liqui-Mix® System. Follow physician's instructions.

Storage & Handling

  • Instructions for Storage:
    • Avoid prolonged exposure of bottles to light.
    • Store unopened at room temperature; avoid extreme temperatures.
    • For mixing: pour, recap, refrigerate and use within 24 hours.
    • Do not reuse bottle.

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