Similac Total Comfort™

Similac Total Comfort™

Partially Hydrolyzed Protein Infant Formula with Iron
  • A 19 Cal/fl oz, nutritionally complete infant formula with partially hydrolyzed whey protein that is an alternative to standard milk-based formulas with intact protein. For mild tolerance symptoms such as fussiness and gas due to lactose sensitivity.

  • OptiGRO™ is our exclusive blend of DHA, lutein and vitamin E: these important ingredients are found in breast milk.
    • DHA for brain and eye development.
    • Lutein to support eye health.
    • Vitamin E, an important nutrient found in breast milk to support developing cells.
  • Our exclusive formula has:
    • Partially hydrolyzed protein for easy digestion.
    • A unique blend of two carbohydrates to help maximize asorption and minimize malabsorption risks.
    • Calcium for strong bones - no palm olein oil.
    • Nucleotides to help support the immune system.
    • Prebiotics to help promote digestive health.
  • Clinically shown to support normal infant growth.1
  • Gluten-free.
  • Halal.
  • Kosher.


  • Consult physician prior to switching formulas.
  • Never use a microwave oven to warm formula. Serious burns can result.
  • Powdered infant formulas are not sterile and should not be fed to premature infants or infants who might have immune problems unless directed and supervised by your baby's doctor.
  • Not for infants or children with galactosemia.
1 Borschel MW, et al. Clin Pediatr 2014;53:1375-1382.
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List Number Item
62599 Similac Total Comfort Powder / 12.0-oz (340-g) can / 6 ct


Unflavored Powder

  • Similac Total Comfort Powder / 12.0-oz (340-g) can / 6 ct

Serving Size: 100 Cal (5.3 fl oz, prepared as directed)

Amount Per Serving % DV % RDI
Nutrient Data
Calories: 100    
Volume, mL: 155.5    
Protein, g: 2.32    
Fat, g: 5.4    
Carbohydrate, g: 11    
Water, g: 140    
Linoleic Acid, mg: 1000    
Vitamin A, IU: 300    
Vitamin D, IU: 60    
Vitamin E, IU: 1.5    
Vitamin K, mcg: 8    
Thiamin (Vitamin B1), mcg: 100    
Riboflavin (Vitamin B2), mcg: 160    
Vitamin B6, mcg: 63    
Vitamin B12, mcg: 0.26    
Niacin, mcg: 1100    
Folic Acid (Folacin), mcg: 16    
Pantothenic Acid, mcg: 470    
Biotin, mcg: 4.6    
Vitamin C (Ascorbic Acid), mg: 9    
Choline, mg: 24    
Inositol, mg: 4.5    
Calcium, mg: 105    
Calcium, mEq: 5.3    
Phosphorus, mg: 70    
Magnesium, mg: 6    
Iron, mg: 1.9    
Zinc, mg: 0.79    
Manganese, mcg: 5    
Copper, mcg: 95    
Iodine, mcg: 9    
Selenium, mcg: 2    
Sodium, mg: 46    
Sodium, mEq: 2    
Potassium, mg: 121    
Potassium, mEq: 3.1    
Chloride, mg: 68    
Chloride, mEq: 1.9    

Serving Size: 1000 mL (1.1 QT, prepared as directed)

Amount Per Serving % DV % RDI
Nutrient Data
Calories: 643    
Volume, mL: 1000    
Protein, g: 14.92    
Fat, g: 34.73    
Carbohydrate, g: 70.7    
Water, g: 900    
Linoleic Acid, mg: 6431    
Vitamin A, IU: 1929    
Vitamin D, IU: 386    
Vitamin E, IU: 9.6    
Vitamin K, mcg: 51    
Thiamin (Vitamin B1), mcg: 643    
Riboflavin (Vitamin B2), mcg: 1029    
Vitamin B6, mcg: 405    
Vitamin B12, mcg: 1.67    
Niacin, mcg: 7074    
Folic Acid (Folacin), mcg: 103    
Pantothenic Acid, mcg: 3023    
Biotin, mcg: 29.6    
Vitamin C (Ascorbic Acid), mg: 58    
Choline, mg: 154    
Inositol, mg: 28.9    
Calcium, mg: 675    
Calcium, mEq: 33.8    
Phosphorus, mg: 450    
Magnesium, mg: 39    
Iron, mg: 12.2    
Zinc, mg: 5.08    
Manganese, mcg: 32    
Copper, mcg: 611    
Iodine, mcg: 58    
Selenium, mcg: 13    
Sodium, mg: 296    
Sodium, mEq: 12.9    
Potassium, mg: 778    
Potassium, mEq: 20    
Chloride, mg: 437    
Chloride, mEq: 12.2    

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Unflavored Powder

  • Similac Total Comfort Powder / 12.0-oz (340-g) can / 6 ct

Maltodextrin, Whey Protein Hydrolysate, High Oleic Safflower Oil, Sugar, Soy Oil, Coconut Oil, Galactooligosaccharides. Less than 2% of: C. Cohnii Oil, M. Alpina Oil, Beta-Carotene, Lutein, Lycopene, Calcium Citrate, Potassium Phosphate, Calcium Phosphate, Magnesium Chloride, Salt, Potassium Citrate, Ascorbic Acid, Choline Chloride, Sodium Citrate, Potassium Chloride, Calcium Hydroxide, Ferrous Sulfate, Choline Bitartrate, Taurine, m-Inositol, Zinc Sulfate, Ascorbyl Palmitate, L-Carnitine, Niacinamide, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Vitamin A Palmitate, Cupric Sulfate, Thiamine Chloride Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Potassium Iodide, Biotin, Sodium Selenate, Vitamin D3, Cyanocobalamin, Potassium Hydroxide, and Nucleotides (Adenosine 5’-Monophosphate, Cytidine 5’-Monophosphate, Disodium Guanosine 5’-Monophosphate, Disodium Uridine 5’-Monophosphate).
Contains milk ingredients.
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  • Ready to Feed
    Ready to feed formula if mixed with water may not provide proper nutrition, and repeated use of such feedings could cause illness.
    • Do not use if breakaway ring is missing or broken.
    • Do not add water.
    • Shake very well.
    • Twist off cap.
    • Twist on nipple and ring.
      • Use clean hands to attach nipple and ring.
      • Use sterile nipple and ring if directed.
    • Once feeding begins, use within 1 hour or discard.

  • Powder

    Your baby's health depends on carefully following these directions. Proper hygiene, handling and storage are important when preparing infant formula. Failure to follow these directions could result in severe harm. Ask your baby's doctor if you need to use cooled, boiled water for mixing and if you need to boil (sterilize) bottles, nipples and rings before use.
    • Wash your hands, surfaces and utensils.
    • Pour water into clean bottle (see mixing guide).
    • Add 1 unpacked level scoop (8.4 g) to each 2 fl oz of water.
    • Return dry scoop to container.
    • Cap bottle; shake well; attach nipple.
    • Once feeding begins, use within 1 hour or discard.

    Powder Mixing Guide

    Measure water+Add scoop(s) of unpacked level powder using enclosed scoop=Finished bottle
    2 fl oz 1 scoop (8.4 g) 2 fl oz
    4 fl oz 2 scoops 4 fl oz
    6 fl oz 3 scoops 6 fl oz
    8 fl oz 4 scoops 8 fl oz

    Pour prepared formula into feeding bottle, cap and store in refrigerator. Use within 24 hours.

Storage & Handling

  • Ready to Feed
    • Avoid prolonged exposure of bottles to light.
    • Store unopened containers at room temperature; avoid extreme temperatures.
    • Do not reuse bottle.
  • Powder
    • Once mixed, store bottles in refrigerator and feed to baby within 24 hours.
    • Store unopened or opened container at room temperature; avoid extreme temperatures.
    • Use opened can contents within 1 month.
    • Do not reuse container.

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