Similac® Human Milk Fortifier Concentrated Liquid

Similac^® Human Milk Fortifier Concentrated Liquid

Similac<sup>®</sup> Human Milk Fortifier Concentrated Liquid

Similac^® Human Milk Fortifier Concentrated Liquid

SIMILAC HUMAN MILK FORTIFIER CONCENTRATED LIQUID is intended for premature and low-birth-weight infants as a nutritional supplement to add to human milk. Use under medical supervision.

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Hospitals and institutions can order Abbott Nutrition products by calling 800-551-5838, Monday – Friday, 8:00 a.m. to 5:30 p.m. EST.

Established Abbott accounts can order online at e-Abbott.com.

Values listed below are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

List Number	Item	Market
56649	Similac Human Milk Fortifier Concentrated Liquid / 0.17 fl oz (5 mL) Packet / 6 x 24 ct	Institutional

Hospitals and institutions can order Abbott Nutrition products by calling 800-551-5838, Monday – Friday, 8:00 a.m. to 5:30 p.m. EST.

5 mL (1 Packet)

Nutrition Data

	Amount Per Serving	%DV
Calories	7
Volume, mL	5
Protein, g	0.35
Fat, g	0.27
Carbohydrate, g	0.81
Water, g	3.6
Linoleic Acid, mg	1
Potential Renal Solute Load, mOsm	3.8
Osmolality, mOsm/kg H2O	NA

Vitamins

	Amount Per Serving	%DV
Vitamin A, IU	197
Vitamin D, IU	35
Vitamin E, IU	1.0
Vitamin K, mcg	2.4
Thiamin (Vitamin B1), mcg	48
Riboflavin (Vitamin B2), mcg	123
Vitamin B6, mcg	49
Vitamin B12, mcg	0.08
Niacin, mcg	1040
Folic Acid (Folacin), mcg	7
Pantothenic Acid, mcg	309
Biotin, mcg	7.6
Vitamin C (Ascorbic Acid), mg	7.7
Choline, mg	0.9
Inositol, mg	1.7

Minerals

	Amount Per Serving	%DV
Calcium, mg	35
Calcium, mEq	1.8
Phosphorus, mg	20
Magnesium, mg	2.2
Iron, mg	0.11
Zinc, mg	0.3
Manganese, mcg	2.1
Copper, mcg	15
Iodine, mcg	0.5
Selenium, mcg	0.2
Sodium, mg	5
Sodium, mEq	0.22
Potassium, mg	21
Potassium, mEq	0.54
Chloride, mg	13
Chloride, mEq	0.37

30 mL (1 packet mixed with 25 mL preterm human milk)

Nutrition Data

	Amount Per Serving	%DV*
Calories	24
Volume, mL	30
Protein, g	0.70
Fat, g	1.24
Carbohydrate, g	2.47
Water, g	25.6
Linoleic Acid, mg	93†
Potential Renal Solute Load, mOsm	6.9
Osmolality, mOsm/kg H2O	385

Vitamins

	Amount Per Serving	%DV*
Vitamin A, IU	294
Vitamin D, IU	35
Vitamin E, IU	1.2
Vitamin K, mcg	2.5
Thiamin (Vitamin B1), mcg	53
Riboflavin (Vitamin B2), mcg	135
Vitamin B6, mcg	53
Vitamin B12, mcg	0.09
Niacin, mcg	1080
Folic Acid, mcg	8
Pantothenic Acid, mcg	354
Biotin, mcg	7.7†
Vitamin C (Ascorbic Acid), mg	10.4
Choline, mg	3.3†
Inositol, mg	5.4†

Minerals

	Amount Per Serving	%DV*
Calcium, mg	41
Calcium, mEq	2.1
Phosphorus, mg	23
Magnesium, mg	2.9
Iron, mg	0.14
Zinc, mg	0.39
Manganese, mcg	2.3†
Copper, mcg	31
Iodine, mcg	3.2†
Selenium, mcg	0.6†
Sodium, mg	12
Sodium, mEq	0.5
Potassium, mg	35
Potassium, mEq	0.9
Chloride, mg	27
Chloride, mEq	0.8

^*One packet (5 mL) Similac Human Milk Fortifier Concentrated Liquid in 25 mL preterm human milk. Preterm human milk values from "Meeting the Special Needs of Low-Birth-Weight and Premature Infants in the Hospital." Columbus, OH: Abbott Nutrition, Abbott Laboratories, Jan 1998, p 56.

^†Values based on term human milk from American Academy of Pediatrics.. "Pediatric Nutrition Handbook", ed 4. Elk Grove Village: American Academy of Pediatrics, 1998, pp 217, 258, 655-658.

100 mL

Nutrition Data

	Amount Per Serving	%DV
Calories	79
Volume, mL	100
Protein, g	2.34
Fat, g	4.14
Carbohydrate, g	8.24
Water, g	85
Linoleic Acid, mg	311
Potential Renal Solute Load, mOsm	23
Osmolality, mOsm/kg H2O	385

Vitamins

	Amount Per Serving	%DV
Vitamin A, IU	982
Vitamin D, IU	118
Vitamin E, IU	4.2
Vitamin K, mcg	8.2
Thiamin (Vitamin B1), mcg	177
Riboflavin (Vitamin B2), mcg	450
Vitamin B6, mcg	176
Vitamin B12, mcg	0.31
Niacin, mcg	3592
Folic Acid, mcg	26.1
Pantothenic Acid, mcg	1180
Biotin, mcg	25.7
Vitamin C (Ascorbic Acid), mg	34.6
Choline, mg	10.8
Inositol, mg	18

Minerals

	Amount Per Serving	%DV
Calcium, mg	137
Calcium, mEq	7
Phosphorus, mg	77
Magnesium, mg	9.9
Iron, mg	0.47
Zinc, mg	1.3
Manganese, mcg	7.5
Copper, mcg	104
Iodine, mcg	11
Selenium, mcg	2
Sodium, mg	37
Sodium, mEq	1.7
Potassium, mg	118
Potassium, mEq	3
Chloride, mg	89
Chloride, mEq	2.6

100 Cal (~4 packets mixed with 100 mL preterm human milk)

Nutrition Data

	Amount Per Serving	%DV*
Calories	100
Volume, mL	126
Protein, g	2.95
Fat, g	5.23
Carbohydrate, g	10.4
Water, g	108
Linoleic Acid, mg	392
Potential Renal Solute Load, mOsm	29
Osmolality, mOsm/kg H2O	385

Vitamins

	Amount Per Serving	%DV*
Vitamin A, IU	1238
Vitamin D, IU	149
Vitamin E, IU	5.3
Vitamin K, mcg	10.3
Thiamin (Vitamin B1), mcg	224
Riboflavin (Vitamin B2), mcg	568
Vitamin B6, mcg	222
Vitamin B12, mcg	0.39
Niacin, mcg	4532
Folic Acid, mcg	32.9
Pantothenic Acid, mcg	1489
Biotin, mcg	32.4
Vitamin C (Ascorbic Acid), mg	43.7
Choline, mg	13.7
Inositol, mg	22.7

Minerals

	Amount Per Serving	%DV*
Calcium, mg	173
Calcium, mEq	8.9
Phosphorus, mg	98
Magnesium, mg	12.5
Iron, mg	0.59
Zinc, mg	1.62
Manganese, mcg	9.5
Copper, mcg	131
Iodine, mcg	13
Selenium, mcg	2
Sodium, mg	47
Sodium, mEq	2.1
Potassium, mg	148
Potassium, mEq	3.8
Chloride, mg	113
Chloride, mEq	3.2

^*Per 100 Calories, as mixed, 4 packets added to 100 mL preterm human milk. Preterm human milk values from Meeting the Special Needs of Low-Birth-Weight and Premature Infants in the Hospital (A8100). Columbus, OH: Abbott, Abbott Laboratories, January 1998.

^†Values based on term human milk from American Academy of Pediatrics.. "Pediatric Nutrition Handbook", ed 4. Elk Grove Village: American Academy of Pediatrics, 1998, pp 217, 258, 655-658.

Features

Small, convenient packet is designed for easy mixing.

For fortifying preterm human milk; has the full range of essential vitamins and minerals.¹

Commercially sterile and meets the Academy of Nutrition and Dietetics and Centers for Disease Control and Prevention (CDC) recommendation to use liquid for NICU feedings.^2,3

Packet is simple to open.⁴

Low iron level provides flexibility to add iron as needed.

Halal.

Kosher; made with dairy ingredients.

Precautions

Add only to human milk - do not add water.

Unless directed by a physician, this formula is not intended for feeding low-birth-weight infants after achieving a body weight of 3600 g (approximately 8 lbs)

This product is nutritionally incomplete by itself and is designed to be added to human breast milk.

Additional iron may be necessary.

Tolerance to enteral feedings should be confirmed by offering small volumes of unfortified human milk.

Once enteral feeding is well established, Similac Human Milk Fortifier Concentrated Liquid can be added to human milk.

Follow directions as specified on carton. Improper dilution may be harmful.

Never use a microwave oven to warm feedings. Serious burns can result.

¹ Klein CJ. J Nutr. 2002;132(6):1395S-1577S.

² Centers for Disease Control and Prevention. Enterobacter sakazakii infections associated with the use of powdered infant formula—Tennessee, 2001. Available at http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5114a1.htm. Published April 11, 2002. Accessed May 31, 2024.

³ Pediatric Nutrition Practice Group. Steele C, Collins E (eds). Infant and Pediatric Feedings: Guidelines for Preparation of Human Milk and Formula in Health Care Facilities, 3rd Ed. Academy of Nutrition and Dietetics. 2019:12.

⁴ Data on file, 2010. Abbott Nutrition Market Research, Abbott Laboratories, Columbus, Ohio.

Unflavored Concentrated Liquid

Water, Nonfat Milk, Corn Syrup Solids, Medium Chain Triglycerides, Whey Protein Concentrate. Less than 2% of: Calcium Phosphate, Magnesium Chloride, Potassium Citrate, Salt, Calcium Carbonate, Potassium Phosphate, Sodium Citrate, Magnesium Phosphate, Zinc Sulfate, Ferrous Sulfate, Copper Sulfate, Manganese Sulfate, Sodium Selenate, Vitamin A Palmitate, Vitamin D3, d-Alpha-Tocopheryl Acetate, Phylloquinone, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Vitamin B12, Niacinamide, Folic Acid, Calcium Pantothenate, Biotin, Ascorbic Acid, Inositol, Choline Chloride, Soy Lecithin, M. Alpina Oil*, Schizochytrium Sp. Oil†, and Potassium Hydroxide.
* Source of ARA.
† Source of DHA.

Contains milk and soy ingredients.

Preparation

INSTRUCTIONS FOR USE:

This product is for premature and low-birth-weight infants. Proper hygiene, handling and storage are important when preparing fortified human milk. Follow directions as specified. Improper dilution may be harmful.

Additional Calories Desired	Human Milk	Similac Human Milk Fortifier	Approximate Yield
2 Calories/fl oz	50 mL	1 packet	55 mL
4 Calories/fl oz	25 mL	1 packet	30 mL

Immediate Use

Pour desired quantity of human milk into sterile feeding container.
Product separation is normal. Massage contents until uniform.
To open packet, tear top off completely along perforation.
Add contents to human milk and shake until mixed well. Once bottle feeding begins, use within one hour or discard.

When Stored

Divide unused fortified human milk into individual bottles or syringes. Refrigerate and use within 24 hours.
After refrigeration, warm to room temperature.
Settling may occur; shake for 10 seconds or until mixed well. Feed promptly.
For syringes, allow 5 mL headspace for mixing. Feed vertically, tip down.

Storage & Handling

STORAGE AND HANDLING:

• Product is light sensitive. Keep unopened in closed carton at room temperature; avoid extreme temperatures.