• Nutrition
Similac® Advance® - Unflavored

Similac® Advance®

Infant Formula with Iron

A 19 Cal/fl oz, nutritionally complete, milk-based, iron-fortified infant formula for use as a supplement or alternative to breastfeeding.


Hospitals and other institutions can order Abbott Nutrition products by calling toll-free, (800) 551-5838, Monday through Friday, 8:00 a.m. to 5:30 p.m. EST.

AVAILABILITY

LIST NUMBER
ITEM
58585
Similac Advance Powder / 1.93-LB (873-g) can / 6 ct
53359
Similac Advance Powder / 1.45-LB (658-g) SimplePac / 6 ct
53496
Similac Advance Powder / 2.13-LB (964-g) SimplePac / 6 ct
63362
Similac Advance Powder / 1.93-LB (873-kg) can / 4 ct
64452
Similac Advance Powder / 2.25-LB (1.02-kg) SimplePac / 3 ct
66330
Sim Advance Powder / 2.5-LB (1.13-kg) can / 6 ct
LIST NUMBER
ITEM
63375
Similac Advance Powder / 2.51-LB (1.41-kg) can / 6 ct

FEATURES

  • OptiGRO™ is our exclusive blend of DHA, lutein and vitamin E: these important ingredients are found in breast milk.
    • DHA for brain and eye development.
    • Lutein to support eye health.
    • Vitamin E, an important nutrient found in breast milk to support developing cells.
  • Our exclusive formula has:
    • Calcium for strong bones - no palm olein oil.
    • Nucleotides to help support the immune system.
    • Prebiotics to help promote digestive health.
    • Carotenoids like those naturally found in breast milk.
  • Clinically proven tolerance in newborns.1
  • Clinically shown to support greater calcium absorption* for strong bones.2,3
  • Gluten-free.
  • Halal.
  • Kosher.

PRECAUTIONS

  • Never use a microwave oven to warm formula. Serious burns can result.
  • Powdered infant formulas are not sterile and should not be fed to premature infants or infants who might have immune problems unless directed and supervised by your baby's doctor.
  • Not for infants or children with galactosemia.

* Similac® with Iron vs Enfamil® with Iron. Enfamil is not a trademark of Abbott Laboratories.

1 Lloyd B, et al. Pediatrics 1999;103:1-6.

2 Nelson SE, et al. J Am Coll Nutr 1998;17(4)327-332.

3 Koo W, et al. Pediatrics 2003;111:1017.

PREPARATION

  • Powder

    Your baby's health depends on carefully following these directions. Proper hygiene, handling and storage are important when preparing infant formula. Failure to follow these directions could result in severe harm. Ask your baby's doctor if you need to use cooled, boiled water for mixing and if you need to boil (sterilize) bottles, nipples and rings before use.
    • Wash your hands, surfaces and utensils.
    • Pour water into clean bottle (see mixing guide).
    • Add 1 unpacked level scoop (8.3 g) to each 2 fl oz of water.
    • Return dry scoop to container.
    • Cap bottle; shake well; attach nipple.
    • Once feeding begins, use within 1 hour or discard.

    Powder Mixing Guide

    Measure water+Add scoop(s) of unpacked level powder using enclosed scoop=Finished bottle
    (approx)
    2 fl oz 1 scoop (8.3 g) 2 fl oz
    4 fl oz 2 scoops 4 fl oz
    6 fl oz 3 scoops 6 fl oz
    8 fl oz 4 scoops 8 fl oz

  • Ready to Feed

    Your baby's health depends on carefully following these directions. Ask your baby's doctor if you need to boil (sterilize) bottles, nipples and rings before use.
    • Do not use if breakaway ring is missing or broken.
    • Do not add water.
    • Shake very well.
    • Twist off cap.
    • Twist on nipple and ring.
    • No need to warm before feeding.
    • Once feeding begins, use within 1 hour or discard.

Storage & Handling

  • Powder
    • Once mixed, store bottles in refrigerator and feed to baby within 24 hours.
    • Store unopened or opened container at room temperature; avoid extreme temperatures.
    • Use opened can contents within 1 month.
    • Do not reuse container.
  • Ready to Feed
    • Store unopened containers at room temperature; avoid extreme temperatures.
    • Do not reuse bottle.
    • Protect from light.
    • Store in carton until ready to use.

NUTRITION

Unflavored Powder

  • Similac Advance Powder / 1.93-LB (873-g) can / 6 ct
  • Similac Advance Powder / 1.45-LB (658-g) SimplePac / 6 ct
  • Similac Advance Powder / 2.13-LB (964-g) SimplePac / 6 ct
  • Similac Advance Powder / 1.93-LB (873-kg) can / 4 ct
  • Similac Advance Powder / 2.25-LB (1.02-kg) SimplePac / 3 ct
  • Sim Advance Powder / 2.5-LB (1.13-kg) can / 6 ct

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

  • Amount per Serving
  • % DV
  • % RDI
  • Nutrient Data
  • Calories
  • 100
  •  
  •  
  • Volume, mL
  • 155.5
  •  
  •  
  • Protein, g
  • 2.07
  •  
  •  
  • Fat, g
  • 5.60
  •  
  •  
  • Carbohydrate, g
  • 10.7
  •  
  •  
  • Water, g
  • 141
  •  
  •  
  • Linoleic Acid, mg
  • 1000
  •  
  •  
  • Vitamins
  • Vitamin A, IU
  • 300
  •  
  •  
  • Vitamin D, IU
  • 75
  •  
  •  
  • Vitamin E, IU
  • 1.5
  •  
  •  
  • Vitamin K, mcg
  • 8
  •  
  •  
  • Thiamin (Vitamin B1), mcg
  • 100
  •  
  •  
  • Riboflavin (Vitamin B2), mcg
  • 160
  •  
  •  
  • Vitamin B6, mcg
  • 63
  •  
  •  
  • Vitamin B12, mcg
  • 0.26
  •  
  •  
  • Niacin, mcg
  • 1100
  •  
  •  
  • Folic Acid (Folacin), mcg
  • 16
  •  
  •  
  • Pantothenic Acid, mcg
  • 470
  •  
  •  
  • Biotin, mcg
  • 4.6
  •  
  •  
  • Vitamin C (Ascorbic Acid), mg
  • 9
  •  
  •  
  • Choline, mg
  • 24
  •  
  •  
  • Inositol, mg
  • 4.9
  •  
  •  
  • Minerals
  • Calcium, mg
  • 82
  •  
  •  
  • Calcium, mEq
  • 4.1
  •  
  •  
  • Phosphorus, mg
  • 44
  •  
  •  
  • Magnesium, mg
  • 6
  •  
  •  
  • Iron, mg
  • 1.9
  •  
  •  
  • Zinc, mg
  • 0.79
  •  
  •  
  • Manganese, mcg
  • 5
  •  
  •  
  • Copper, mcg
  • 95
  •  
  •  
  • Iodine, mcg
  • 6
  •  
  •  
  • Selenium, mcg
  • 2
  •  
  •  
  • Sodium, mg
  • 25
  •  
  •  
  • Sodium, mEq
  • 1.1
  •  
  •  
  • Potassium, mg
  • 110
  •  
  •  
  • Potassium, mEq
  • 2.8
  •  
  •  
  • Chloride, mg
  • 68
  •  
  •  
  • Chloride, mEq
  • 1.9
  •  
  •  

Unflavored Powder

  • Similac Advance Powder / 1.93-LB (873-g) can / 6 ct
  • Similac Advance Powder / 1.45-LB (658-g) SimplePac / 6 ct
  • Similac Advance Powder / 2.13-LB (964-g) SimplePac / 6 ct
  • Similac Advance Powder / 1.93-LB (873-kg) can / 4 ct
  • Similac Advance Powder / 2.25-LB (1.02-kg) SimplePac / 3 ct
  • Sim Advance Powder / 2.5-LB (1.13-kg) can / 6 ct

Serving size: 1000 mL (1.1 QT, prepared as directed)

  • Amount per Serving
  • % DV
  • % RDI
  • Nutrient Data
  • Calories
  • 643
  •  
  •  
  • Volume, mL
  • 1000
  •  
  •  
  • Protein, g
  • 13.31
  •  
  •  
  • Fat, g
  • 36.2
  •  
  •  
  • Carbohydrate, g
  • 69.2
  •  
  •  
  • Water, g
  • 906
  •  
  •  
  • Linoleic Acid, mg
  • 6431
  •  
  •  
  • Vitamins
  • Vitamin A, IU
  • 1929
  •  
  •  
  • Vitamin D, IU
  • 482
  •  
  •  
  • Vitamin E, IU
  • 9.6
  •  
  •  
  • Vitamin K, mcg
  • 51
  •  
  •  
  • Thiamin (Vitamin B1), mcg
  • 643
  •  
  •  
  • Riboflavin (Vitamin B2), mcg
  • 1029
  •  
  •  
  • Vitamin B6, mcg
  • 405
  •  
  •  
  • Vitamin B12, mcg
  • 1.67
  •  
  •  
  • Niacin, mcg
  • 7074
  •  
  •  
  • Folic Acid (Folacin), mcg
  • 103
  •  
  •  
  • Pantothenic Acid, mcg
  • 3023
  •  
  •  
  • Biotin, mcg
  • 29.6
  •  
  •  
  • Vitamin C (Ascorbic Acid), mg
  • 58
  •  
  •  
  • Choline, mg
  • 154
  •  
  •  
  • Inositol, mg
  • 31.5
  •  
  •  
  • Minerals
  • Calcium, mg
  • 527
  •  
  •  
  • Calcium, mEq
  • 26.4
  •  
  •  
  • Phosphorus, mg
  • 283
  •  
  •  
  • Magnesium, mg
  • 39
  •  
  •  
  • Iron, mg
  • 12.2
  •  
  •  
  • Zinc, mg
  • 5.08
  •  
  •  
  • Manganese, mcg
  • 32
  •  
  •  
  • Copper, mcg
  • 611
  •  
  •  
  • Iodine, mcg
  • 39
  •  
  •  
  • Selenium, mcg
  • 13
  •  
  •  
  • Sodium, mg
  • 161
  •  
  •  
  • Sodium, mEq
  • 7.1
  •  
  •  
  • Potassium, mg
  • 707
  •  
  •  
  • Potassium, mEq
  • 18
  •  
  •  
  • Chloride, mg
  • 437
  •  
  •  
  • Chloride, mEq
  • 12.2
  •  
  •  

Unflavored Powder

  • Similac Advance Powder / 2.51-LB (1.41-kg) can / 6 ct

Serving size: 100 Cal (5.3 fl oz, prepared as directed)

  • Amount per Serving
  • % DV
  • % RDI
  • Nutrient Data
  • Calories
  • 100
  •  
  •  
  • Volume, mL
  • 155.5
  •  
  •  
  • Protein, g
  • 2.2
  •  
  •  
  • Fat, g
  • 5.6
  •  
  •  
  • Carbohydrate, g
  • 10.6
  •  
  •  
  • Water, g
  • 141
  •  
  •  
  • Linoleic Acid, mg
  • 1000
  •  
  •  
  • Vitamins
  • Vitamin A, IU
  • 300
  •  
  •  
  • Vitamin D, IU
  • 75
  •  
  •  
  • Vitamin E, IU
  • 1.5
  •  
  •  
  • Vitamin K, mcg
  • 8
  •  
  •  
  • Thiamin (Vitamin B1), mcg
  • 100
  •  
  •  
  • Riboflavin (Vitamin B2), mcg
  • 160
  •  
  •  
  • Vitamin B6, mcg
  • 63
  •  
  •  
  • Vitamin B12, mcg
  • 0.26
  •  
  •  
  • Niacin, mcg
  • 1100
  •  
  •  
  • Folic Acid (Folacin), mcg
  • 16
  •  
  •  
  • Pantothenic Acid, mcg
  • 470
  •  
  •  
  • Biotin, mcg
  • 4.6
  •  
  •  
  • Vitamin C (Ascorbic Acid), mg
  • 12
  •  
  •  
  • Choline, mg
  • 24
  •  
  •  
  • Inositol, mg
  • 4.9
  •  
  •  
  • Minerals
  • Calcium, mg
  • 118
  •  
  •  
  • Calcium, mEq
  • 5.9
  •  
  •  
  • Phosphorus, mg
  • 64
  •  
  •  
  • Magnesium, mg
  • 6
  •  
  •  
  • Iron, mg
  • 1.9
  •  
  •  
  • Zinc, mg
  • 0.79
  •  
  •  
  • Manganese, mcg
  • 5
  •  
  •  
  • Copper, mcg
  • 95
  •  
  •  
  • Iodine, mcg
  • 6
  •  
  •  
  • Selenium, mcg
  • 2
  •  
  •  
  • Sodium, mg
  • 25
  •  
  •  
  • Sodium, mEq
  • 1.1
  •  
  •  
  • Potassium, mg
  • 110
  •  
  •  
  • Potassium, mEq
  • 2.8
  •  
  •  
  • Chloride, mg
  • 68
  •  
  •  
  • Chloride, mEq
  • 1.9
  •  
  •  

Unflavored Powder

  • Similac Advance Powder / 2.51-LB (1.41-kg) can / 6 ct

Serving size: 1000 mL (1.1 QT, prepared as directed)

  • Amount per Serving
  • % DV
  • % RDI
  • Nutrient Data
  • Calories
  • 643
  •  
  •  
  • Volume, mL
  • 1000
  •  
  •  
  • Protein, g
  • 14.15
  •  
  •  
  • Fat, g
  • 36.01
  •  
  •  
  • Carbohydrate, g
  • 68.17
  •  
  •  
  • Water, g
  • 907
  •  
  •  
  • Linoleic Acid, mg
  • 6431
  •  
  •  
  • Vitamins
  • Vitamin A, IU
  • 1929
  •  
  •  
  • Vitamin D, IU
  • 482
  •  
  •  
  • Vitamin E, IU
  • 9.6
  •  
  •  
  • Vitamin K, mcg
  • 51.4
  •  
  •  
  • Thiamin (Vitamin B1), mcg
  • 643
  •  
  •  
  • Riboflavin (Vitamin B2), mcg
  • 1029
  •  
  •  
  • Vitamin B6, mcg
  • 405
  •  
  •  
  • Vitamin B12, mcg
  • 1.67
  •  
  •  
  • Niacin, mcg
  • 7074
  •  
  •  
  • Folic Acid (Folacin), mcg
  • 102.9
  •  
  •  
  • Pantothenic Acid, mcg
  • 3023
  •  
  •  
  • Biotin, mcg
  • 29.6
  •  
  •  
  • Vitamin C (Ascorbic Acid), mg
  • 77.2
  •  
  •  
  • Choline, mg
  • 154.3
  •  
  •  
  • Inositol, mg
  • 31.5
  •  
  •  
  • Minerals
  • Calcium, mg
  • 759
  •  
  •  
  • Calcium, mEq
  • 37.9
  •  
  •  
  • Phosphorus, mg
  • 412
  •  
  •  
  • Magnesium, mg
  • 38.6
  •  
  •  
  • Iron, mg
  • 12.2
  •  
  •  
  • Zinc, mg
  • 5.08
  •  
  •  
  • Manganese, mcg
  • 32.2
  •  
  •  
  • Copper, mcg
  • 611
  •  
  •  
  • Iodine, mcg
  • 39
  •  
  •  
  • Selenium, mcg
  • 13
  •  
  •  
  • Sodium, mg
  • 161
  •  
  •  
  • Sodium, mEq
  • 7.1
  •  
  •  
  • Potassium, mg
  • 707
  •  
  •  
  • Potassium, mEq
  • 18
  •  
  •  
  • Chloride, mg
  • 437
  •  
  •  
  • Chloride, mEq
  • 12.2
  •  
  •  

INGREDIENTS

Unflavored Powder

  • Similac Advance Powder / 1.93-LB (873-g) can / 6 ct
  • Similac Advance Powder / 1.45-LB (658-g) SimplePac / 6 ct
  • Similac Advance Powder / 2.13-LB (964-g) SimplePac / 6 ct
  • Similac Advance Powder / 1.93-LB (873-kg) can / 4 ct
  • Similac Advance Powder / 2.25-LB (1.02-kg) SimplePac / 3 ct
  • Sim Advance Powder / 2.5-LB (1.13-kg) can / 6 ct

Nonfat Milk, Lactose, Whey Protein Concentrate, High Oleic Safflower Oil, Soy Oil, Coconut Oil, Galactooligosaccharides. Less than 2% of: C. Cohnii Oil, M. Alpina Oil, Beta-Carotene, Lutein, Lycopene, Potassium Citrate, Calcium Carbonate, Ascorbic Acid, Soy Lecithin, Potassium Chloride, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Ascorbyl Palmitate, Salt, Taurine, m-Inositol, Zinc Sulfate, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, L-Carnitine, Vitamin A Palmitate, Cupric Sulfate, Thiamine Chloride Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Cyanocobalamin, Calcium Phosphate, Potassium Phosphate, Potassium Hydroxide, and Nucleotides (Adenosine 5’-Monophosphate, Cytidine 5’-Monophosphate, Disodium Guanosine 5’-Monophosphate, Disodium Uridine 5’-Monophosphate).

Contains milk and soy ingredients.

Unflavored Powder

  • Similac Advance Powder / 2.51-LB (1.41-kg) can / 6 ct

Nonfat Milk, Lactose, Whey Protein Concentrate, High Oleic Safflower Oil, Soy Oil, Coconut Oil, Galactooligosaccharides. Less than 2% of: C. Cohnii Oil, M. Alpina Oil, Beta-Carotene, Lutein, Lycopene, Potassium Citrate, Calcium Carbonate, Ascorbic Acid, Soy Lecithin, Potassium Chloride, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Ascorbyl Palmitate, Salt, Taurine, m-Inositol, Zinc Sulfate, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, L-Carnitine, Vitamin A Palmitate, Cupric Sulfate, Thiamine Chloride Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Cyanocobalamin, Calcium Phosphate, Potassium Phosphate, Potassium Hydroxide, and Nucleotides (Adenosine 5’-Monophosphate, Cytidine 5’-Monophosphate, Disodium Guanosine 5’-Monophosphate, Disodium Uridine 5’-Monophosphate).

Contains milk ingredients.

SUPPORTING MATERIALS

Medicare Rates and HCPCS Codes (PDF 264 KB)

Locate a Sales Rep

If you would like to speak with an Abbott Nutrition sales representative, please contact: 1-800-551-5838.

Let us know your area of specialization and the product you are inquiring about, and our product experts will be happy to assist you.

You can also locate a sales rep via email.